Astrocyte Human Endogenous Retrovirus (HERV) Expression Analysis

Genome version: GRCh38.p13

Volcano Plots:

Chikungunya

Mayaro

Oropouche

Zika

HERV Analysis

Differential Expression perfomed by DESeq2


Upregulated

Downregulated

HERV near genes Analysis

HERVs:


Upregulated

Downregulated

Genes upstream and downstream to the HERV:

Upregulated

Downregulated

Venn Diagram



Upregulated

Downregulated

Upregulated

Downregulated



Upregulated

Downregulated

Upregulated

Downregulated

Reference Annotations (by Telescope)

HERVK(HML-2)

Subramanian RP, Wildschutte JH, Russo C, Coffin JM. 2011. Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses. Retrovirology 8: 90.

HERVW

Grandi N, Cadeddu M, Blomberg J, Tramontano E. 2016. Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes. Retrovirology 13: 67.

Telescope is available at github.com/mlbendall/telescope

Telescope reference Annotation: https://github.com/mlbendall/telescope_annotation_db/tree/master/refs